@Pittmanj, The My Cloud will work with Windows 10. Is this Windows 10 PC on the same local network as the My Cloud, or are you trying to access the My Cloud remotely with Windows 10?
First step is to ensure you have updated Windows 10 with all the latest Microsoft Windows 10 updates. Microsoft pushed out an update on March 1st that fixed one specific issue between the My Cloud and Windows 10.
Second, on computers running later versions of Windows (7, 8, 8.1, 10) there are various settings within Windows that can prevent access to the My Cloud on the local network. This includes having NETBIOS over TCP/IP disabled. Or having the network connection configured for Public rather than Private. The link posted earlier in his thread have the general steps/procedures listed for how to fix those two particular issues. Specifically steps; Windows 10 Specific Method 1 and Windows 10 Specific Method 2 in that link.
Third, do you have another computer, or mobile device that you can use to access the My Cloud on the local network?
Fourth, have you tried any of the WD software programs (WD My Cloud Desktop, WD Discovery, WD Quick View, WD Access) to see if they can find and access the My Cloud on that Windows 10 computer? WD software can be downloaded from the WD Support site: http://supportdownloads.wdc.com/downloads.aspx?lang=en