Safely Ejecting Passport drive doesn't always work

Using Windows 10. When attempting to eject MyPassport drive using Safely Remove Hardware tab, I get a message that says windows can’t eject the drive because another program(s) is using it. I have closed all applications that look like they might still be accessing the drive, but still get the same result. Even performing a shutdown doesn’t work.
How can I figure out what application is preventing me from safely removing the drive so I can then unplug it from my pc and not damage the drive?

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Hello Mopilot827,

Maybe you should try contacting WD’s Technical Support about this.

To Contact WD for Technical Support

http://support.wdc.com/support/case.aspx?lang=en

The link below will allow you to call support:

I have this problem too. I have shut down all apps, and checked Task Manager, and NOTHING is using the drive. And yet it still refuses to be ejected.