Certain Changes made to Twonky, either through the Twonky administration page, or using SSH to tweak the Twonky settings are destroyed/erased when one upgrades the single bay My Cloud firmware.
See the unofficial Twonky FAQ at the following link which has a list of user suggested “best practices” with the Twonky media server.
http://community.wd.com/t/faq-twonky-dlna-media-server-setup-use/95373