If one researches other more advanced My Cloud models they’ll see that App installation including Transmission is possible:
http://support.wdc.com/KnowledgeBase/answer.aspx?ID=11046
See the Setup.WD2Go.com website (http://setup.wd2go.com/) which has more information on the various My Cloud models including which models support installing third party apps. For example the My Cloud Mirror: http://setup.wd2go.com/?mod=faqs&device=mcm&faq=thirdParty