Does your My Cloud have a static IP address? If not assign one either by reserving the IP Address within the router’s DHCP server or assign a fixed IP address through the My Cloud Dashboard > Settings > Network section.
Windows 10 is sometimes quirky with the My Cloud and its more an issue with Windows 10 than the My Cloud. You may want to dig through the following thread to see if anything might solve your issues.
https://community.wd.com/t/compilation-of-windows-10-methods-steps-and-solutions/142576
