Hi there - I haven't done this before so I hope it drops into the conversation where I expect it to.
I have had trouble for a long time with dead slow performance by my Lpatop, and found these posts by luck.
When I looked in Task Manager to see what process was tying up my CPU WDWDFME wasn't visible, but in the Task Manager, there is a 'Performance' tab. If you go into that you will see a button near the bottom that says 'Resource Monitor'.
If you click on that you can see what is chewing up the CPU - if you click on the CPU column it will sort in order of what is using the most. That let me see that it was WDFME.exe chewing up 70% to 95% of my CPU even though the back up drive isn't plugged in.
What you then do is right click on it, and end the process. It aiin't backing up; just stuffing up. Immediately I got control of my computer back and CPU use is bubbling along at 2% and things are humming. I agree with all the posts. What a stupid program to completely neuter your machine when not even needed.
Time to search for another Back up program. I like the drives though and have several doing rotating copies of my 90GB of music and 80GB of photos.
Thanks to all the posts that helped me know what I was looking for.