WD Blue 250GB M.2 does not boot!

Hi,

I have cloned my Win10 OS from a SSD to a WD 250GB M.2 with Acronis True Image.

After going through the routine of checking BIOS boot sequence so on.

It does not boot up Win10, the Win Logo appears but as soon as the dots go round a few times it goes to a black screen with only the mouse pointer visible.

My MB is a Gigabyte X99 sli Bios version F23. I know for a fact that if an M.2 is installed Sata ports 4/5 do not work so I have the Sata drives connected elsewhere.

Any help really appreciated
Thanks