Using RE4 as a "Desktop"-Drive: Problems with SpinUp-Cycles?

If I use a RE4 as a “Desktop”-Drive for home: Is there a problem with the higher count of spinup/shutdown-cycles (3-4/week) ?

I remember times where 24/7 drives cant deal with the home use typical spinup count, so thats why I ask.

Hi if you use a RE drive in your desktop you will get a enterprise drive that is built better and will last longer. The RE drive’s have what they call tler Time Limited Error Recovery this is used in Raid configuration’s but has no impact on running it alone. I have used enterprise drive’s for years as I prefer a good hard drive in my system’s less chance of error. So yes it will work fine.  

Thanks!