Upgrade to 500GB 16MB cache (PATA)

I am replacing a WD800AABB in a 6 yr old desktop.

I’ve done the BiOS upgrade, installed the Intel Accelerator in prep of the new HD.

(I’m a newbie so sorry if this is a stupid question)

My question is the WD5000AAKB has 16MB cache, while the WD80 only 2MB. Is there any limitations, motherboard or system in going with a HD w/16MB cache?

My machine is a Gateway:

Pentium 4  2.6GHz
Intel 850 chipset


thanks is advance__Jeff