I would be happy to run WDS 24/7 if it did what it claims - i.e. to work unobtrusively in the background so you can continue to use your pc. This is not my experience and to my mind its one of the worst products I’ve had the misfortune to buy.
I have a “My Passport Essential” and even when this is not connected I have to tolerate poor performance from my pc for a couple of hours every time I start it up, from what appears to be WDFME using system resources (on what I’ve no idea).
My solution - not to turn my laptop off unless I have to.
If I do feel brave and connect the drive I might as well take the day off from my pc as it completely grinds to a halt. I turn all my applications off, as they’re unusable, and start to back-up. Even this is a trauma, as its then almost impossible to stop as none of the functions appear to work, such as start/stop backup and if you try to “safely eject software” a message comes up saying it can’t - try again later!
My solution: only connect when you don’t need to use your pc.
Quite simply, I think its atrocious and WD may produce the worlds best selling hard drives, as claimed, uits just a pity it can’t produce the s/w to support them.