Use the forum search feature, magnifying glass icon upper right, and search for “unbrick”. There are numerous discussions on how to install a new hard drive in a single bay My Cloud enclosure.
User Fox_Exe has a set of directions for the first gen 4v.x firmware and second gen v2.x firmware single bay/single drive My Cloud units. The directions are slightly different so make sure to use the correct one for your My Cloud model.
First gen: https://drive.google.com/file/d/0B_6OlQ_H0PxVbzZac0plbkZKeGM/view
Firmware file used in first gen directions: https://drive.google.com/drive/folders/0B_6OlQ_H0PxVNTN6c2F4SXEwQVU
Second gen: https://drive.google.com/file/d/0B_6OlQ_H0PxVQVhnLVJOdDZISUU/view
Check the P/N ending number on the bottom of the My Cloud enclosure.
P/N “-00” is first gen.
P/N “-10” is second gen.
You cannot put the older first gen v4.x firmware on the newer second gen v2.x firmware single bay My Cloud units.