Your Error 0x8007045D is common on Vista Ultimate. To reslove:
1) Login as Local Admin.
2) Open System properties. (Computer > Properties > Advance Systems Settings > System Properties > System Protection TAB.
3) On the 'System Protection Tab' identify the Local Hard Disk targeted for Backup. Under 'Available Disks' uncheck the box indicating the last Restore Point, then, select 'Apply' in the lower left corner. Immediately re-check the box next to the 'Available Disks' (you are creating a new Restore Point now) and then select 'Apply' again.
Effectively, what you should have done is cleared the box - applied the change - selected the box- applied the change in that order.
If everything worked as planned you should be able to begin (and COMPLETE) a Full Backup of this targeted Hard Disk.