Disconnect backup drive

Simple question: can I disconnect my WD My Passport Slim drive from my Macbook Pro and then reconnect it later without 

messing up the backup software and schedule? I want to take the Macbook into another part of the house without taking the drive with it.

Yes, you can do that. Just make sure to safely eject the drive before you unplug it.

Check the link below for detailed information on how to safely disconnect the drive.