WDFME.exe RAM hog

well the support page for smartware states

NOTE: To update to this version of WD SmartWare, you need the following minimum requirements:

  • Windows XP 32-bit Service Pack 3, Windows XP 64-bit Service Pack 2, Windows Vista or Windows 7.
  • Microsoft .NET Framework 3.5 or higher installed on your computer.

If you don’t already have the Microsoft .NET Framework 3.5 installed on your computer, you will be prompted to install it.

so having the most current net 3.5 probably is a good idea…