I have been through the DX4000 user guide that somebody linked to and would I be correct in thinking you cannot do automated remote backups from client computers? Also I thought I had read that you could backup Macs as well - is that only using the Mac’s built in Time Machine software?
As far as I now you cannot do automated remote backups, on the Mac side any backup program that can access a shared folder should be able to backup to the Sentinel.