Unfortunately, this is information we are unable to provide.
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Depending on model, the internal hard drive in an external enclosure could be either SATA or native USB.
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We can only guarantee drive capacity. We cannot guarantee a particular internal hard drive model, data interface, rotational speed, or cache size in the external hard drive enclosure.
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Dismantling any single-drive external enclosure to obtain this information will void the warranty of the hard drive.
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Interface and cache of the hard drives inside the external enclosure does not affect the performance or the data transfer rate of the external hard drive unit.
http://wdc.custhelp.com/app/answers/detail/a_id/1704/
On the other hand, yes, the disk drive was designed for constant operation.